Patents & Grants

Funded Research Grants

  1. Study of a Mechanical Impactor as an Endoscopic Lithotriptor. Browne Medical Systems, Inc. Browne Pneumatic Impactor Clinical Study, March 1995. IRB approved study # 6019‑01 – study ended 1999.
  1. Application of Holmium Laser Energy in the Urinary Tract. Coherent Medical Systems, Palo Alto, California, Feb 1995‑1999.
  1. Development of Endoscopic Procedures, Devices, and Techniques for Urology, Obstetrics and Gynecology. Karl Storz Medical Systems, Culver City, California. 1992 – 1997.
  1. Applications of a Variable Pulse Duration Holmium Laser. Xintec Corporation, Oakland, California, 1995 – 1996.
  1. Prospective Randomized trial of ESWL versus PCNL for lower pole renal calculi. Microvasive Inc.  Natick, MA June 1995 ‑ present.  IRB approved study # 9311, updated to include ureteroscopy arm, March 2000 – October 2002.
  1. Study of cyanide production form holmium laser lithotripsy. Coherent Inc., San Francisco, CA, IRB H8063‑01, December 1998 – 1999
  1. Study of new coil ureteral stent design. Boston Scientific, Natick, MA.  October 2001 – 2004. Patent Accepted
  2. Development of Office Based Laser Therapies in Urology. Convergent Laser Systems, Oakland, CA.  October 2001 – 2006.
  1. Development of Suction Laser Application. Boston Scientific, Inc. Natich, Massachusetts. Patent Accepted 2003.
  1. Study of Renal Parenchymal Preservation Agents which minimize hypoxia induce cell death during renal surgery. 2007 – 2016. Susan Schott Research Award.
    1. Michels, C., Dorai, T., Chander, P., Choudhury, M., Grasso, M. – Hypoxic pre-conditioning in a rat renal ischemia model: an evaluation of the use of hydralazine. World Journal of Urology.
    2. Dorai, T., Michels, C., Goldfarb, DS, Grasso, M., – Strategies to extend warm ischemia time during laparoscopic partial nephrectomy – I. International Nephrology Urology.
    3. Dorai, T., Michels, C., Goldfarb, DS., Grasso, M., – Strategies to extend warm ischemia time during laparoscopic partical nephrectomy – II. International Nephrology Urology.
    4. Dorai T, Michels C, Goldfarb DS and Grasso M. Strategies to Extend Warm Ischemia Time in Laparoscopic Partial Nephrectomy: A Review, Part I. International Journal of Nephrology Urology 1 (2) 79-93. 2009
    5. Dorai T, Michels C, Goldfarb DS, and Grasso M. Strategies to Extend Warm Ischemia Time in Laparoscopic Partial Nephrectomy: A Review, Part II. International Journal of Nephrology Urology 2(1) 157-171. 2010
    6. Dorai T, Fishman A, Ding C, Haberle I, Goldfarb D, Grasso M: Amelioration of renal ischemia- reprofusion injury with a novel protective cocktail. J Urol 186, December 2011
    7. Cohen J, Dorai1 T, Ding C, Batinic-Haberle I, Grasso M. An Unique Renoprotective Cocktail Helps In Extending The Warm Ischemia Time In A Rat Model. J Endourol.  Mar;27(3):343-8, 2013
    8. Alexander B, James M, Fishman A, Grasso M, Dorai T. Induction of hypometabolism as a novel strategy to minimize ischemia reperfusion injuries in partial nephrectomies.  2nd Prize Winner Endourology Annual Essay Contest – Basic Science Category. Transplantation Technologies & Research 6:3, 2016
  1. Study of Carbonic Anhydrase 1X Coenzyme in the Progression of Several Renal Cell Carcinoma Subtypes. Funding source: Saint Vincent’s Urology Research Fund and Ladies Auxillary Research Fund of Saint Vincent’s Hospital, Manhattan, NY. 2/02 – 2/08.
  1. Consortium for Hereditary Causes of Nephrolithiasis and Renal Failure (The Rare Kidney Stone Consortium); Project 2: Cystinuria. NIDDK: U54 DK-082908. 9/2009 – 8/2013. PI: Milliner, Mayo Clinic. Role: Key Personnel.
  1. Basic Science Laboratory (Thambi Dorai Ph.D.) moved from St. Vincents Medical Center in Manhattan to the main campus, New York Medical College, Department of Biochemistry, Valhalla, New York. May 2010.
  2. Evaluation of Small Diameter Digital Flexible Ureteroscope (Slim Flex Xc) and comparison with standard instruments. KSEA, 6/2018 – 11/2019. Massachusetts

Director, Fellowship in Endourology

Patents

Sept 16, 2003
Medical Stent with Variable Coils and Related Methods
US Patent 6,620,202

May 2, 2006
Medical Stent with Variable Coil and Related Methods    
US Patent 7,037,345

April 23, 2002 
Laser Lithotripsy Device With Suction                           
US Patent 6,375,651

April 27, 2004 
Laser Lithotripsy Device With Suction              
US Patent 6,726,681

Sept 12, 2006
Laser Lithotripsy Device With Suction
US patent 7,104,983